CompletedPhase 4

hCG Priming in Women With Low Ovarian Reserve

Denmark20 participantsStarted 2020-12-27

Plain-language summary

The aim of this trial is to examine the possible effects of hCG administration for eight weeks prior to IVF/ICSI in women with low ovarian reserve. Primary outcome is the proportion of the antral follicle count that reach the pre-ovulatory stage.

Who can participate

Age range18 Years – 40 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Regular menstrual cycle (23-35 days) * 1.-5. IVF/ICSI cycle at inclusion * AMH \< 6.29 pmol/L (Elecsys® AMH assay) Exclusion Criteria: * Uterine malformations or hydrosalpinx * Submucosal uterine myomas * Uterine polyps * Allergy to standard IVF/ICSI medication * Endometriosis stage III-IV * Severe comorbidity * Preimplantation genetic testing * Testicular sperm aspiration/extraction * Tumors in the hypothalamus or pituitary gland * Active thromboembolic disease

What they're measuring

Follicular output rate

Timeframe: Through study completion, an average of 5 months

Trial details

NCT IDNCT04643925

SponsorRigshospitalet, Denmark

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-08-31

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