WithdrawnNot Applicable

Treating Chronic Pouchitis With a Low FODMAP Diet

Stopped: This study has been stopped due to difficulty with enrollment.

United States0Started 2020-10-27

Plain-language summary

We aim to determine whether low FODMAP diet in patients with chronic pouchitis will improve symptoms and pouch inflammation.

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria * Patients aged 18-65 with a diagnosis of ulcerative colitis that have undergone ileal pouch-anal anastomosis following proctocolectomy for medication-refractory disease * Either ≥4 episodes of pouchitis per year (antibiotic-dependent) OR persistent symptoms despite 4 weeks of antibiotic therapy (antibiotic-resistant) Exclusion Criteria * Diagnosis of indeterminate colitis or Crohn's disease * Celiac disease * Current use of low FODMAP diet * Known dietary allergies * Current use of antibiotics for reasons other than treatment of pouchitis * Clostridium difficile infection * Complication following ileal pouch-anal anastomosis requiring reoperation

What they're measuring

Mean Difference in Fecal Calprotectin

Timeframe: 6 weeks

Trial details

NCT IDNCT04640155

SponsorNorthwestern University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-10-27

View on ClinicalTrials.gov More Pouchitis trials