AD109 Dose Finding in Mild to Moderate OSA

Inclusion Criteria: * AHI between 5 and 20 events/h * PGI-S equal to or higher than 1, or one or more of the following symptoms: * Snoring or nightime gasping/choking * Daytime sleepiness, fatigue or decreased concentration * Nonrefreshing sleep, sleep fragmentation (including from nocturia), or morning headache * Irritability, decreased mood or libido Exclusion Criteria: * History of narcolepsy. * Clinically significant craniofacial malformation. * Clinically significant cardiac disease (e.g. rhythm disturbances, coronary artery disease or heart failure or hypertension requiring more than 2 medications for control). * CPAP should not be used for at least 2 weeks prior to the study * History of using oral or nasal devices for the treatment of OSA may enroll as long as the devices are not used during participation in the study.