CompletedNot Applicable

Melatonin and Hyaluronic Acid in Maxillary Sinus Augmentation

Egypt16 participantsStarted 2019-12-03

Plain-language summary

melatonin proved an ability to repair bone defects and enhance osseointegration of dental implants. Also, hyaluronic acid has osteopromoting properties. the effect of melatonin and hyaluronic acid on the newly formed bone in maxillary sinus augmentation was evaluated

Who can participate

Age range

30 Years – 50 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age range will be between (30 - 50) years old. * Patients with missed one or more of posterior teeth with minimum residual bone height 5 mm * Adequate inter-occlusal space of at least 8 mm Exclusion Criteria: * Maxillary sinus diseases. * Previous sinus surgery like the Caldwell-Luc operation. * History of chemotherapy or radiotherapy to maxilla. * Presence of Underwood's septa/severe sinus floor convolutions. * Systemic disease affecting bone metabolism. * Uncontrolled diabetes mellitus. * Heavy smokers. * Para functional habits.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

change Implant stability

Timeframe: at baseline and 6 months

change in bone density

Timeframe: at baseline, 1 month and 6 months

change in vertical bone height

Timeframe: at baseline, 1 month and 6 months

change in marginal bone level

Timeframe: at baseline, 1 month and 6 months

Trial details

NCT IDNCT04625179

SponsorHams Hamed Abdelrahman

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-12-07

View on ClinicalTrials.gov More Edentulous; Alveolar Process, Atrophy trials

Who can participate

Age range

30 Years – 50 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.