UnknownNot Applicable

The Influence of Antibiotics on the Incidence of Biliary Tract Infections After PTCD for Malignant Obstructive Jaundice

China120 participantsStarted 2020-10-20

Plain-language summary

To investigate the influence of antibiotics on the incidence of biliary tract infections after PTCD for malignant obstructive jaundice.

Age range18 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

✓. 18-80 years old;
✓. ECOG score 0-1 before operation;
✓. Patients diagnosed as pancreatic head cancer and periampullary cancer according to preoperative imaging, including ampullary cancer, extrahepatic bile duct cancer and duodenal papillary cancer;
✓. Bilirubin\>200 mmol/L before PTCD , and the duration of PTCD continuous drainage \>2 weeks;
✓. Volunteer to participate and sign the informed consent form;

✕. Decompensated liver cirrhosis, acute and chronic hepatitis and other diseases before surgery;
✕. A history of other malignant tumors before surgery;
✕. Duration of preoperative PTCD drainage\<2 weeks;
✕. Jaundice caused by other reasons besides cancer around the ampulla and cancer of the head of the pancreas;

Incidence of patients with biliary tract infection after surgery

Timeframe: October 2020 to June 2023

NCT IDNCT04620577

SponsorXian-Jun Yu

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-06-30

Xianjun Yu, PhD