Oral Iron Frequency for Childhood Restless Leg Syndrome/Periodic Limb Movement Disorder

Inclusion Criteria: * Ferritin equal to or lower than 24 mcg/L drawn within the last 30 days. * Age 2 to 10 years. * Diagnosis of restless leg syndrome, periodic limb movement disorder, or sleep disturbance. Exclusion Criteria: * Currently taking oral formulation of iron other than a multivitamin. * Untreated obstructive sleep apnea. * Gastrointestinal disorder, including gastroesophageal reflux disease and celiac disease. * Prior gastrointestinal surgery; e.g., gastrectomy, duodenal bypass, and presence of G-tube. * Use of H2 blocker, antacid, or proton pump inhibitor. * Inflammatory disorders, including juvenile idiopathic arthritis or inflammatory bowel disease. * Elevated CRP at time of initial ferritin or report of illness in past 4 weeks.