CompletedNot Applicable

Blinded Dry Mouth Spray Crossover Study

United States129 participantsStarted 2021-01-14

Plain-language summary

To identify the effectiveness of two mouth sprays at relieving symptoms of xerostomia in patients who have received radiation for carcinoma of the head and neck. To assess patient quality of life and mouth acidity following use of two mouth sprays meant to relieve symptoms of xerostomia in patients who have received radiation for carcinoma of the head and neck.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * biopsy-proven oral cavity, oropharynx, larynx, and hypopharynx carcinoma * who received primary radiation with curative intent (\>50 Gray in 20 fractions) * radiation treatment completed greater than 6 months ago * who endorse xerostomia Exclusion Criteria: * evidence of metastasis or recurrent disease * Current use of pilocarpine, antidepressants, anticholinergic drugs, or any other medication that has an effect on salivation * those who have documented medical conditions associated with xerostomia such as Sjogren's Syndrome * those who use oral inhalants for the treatment of respiratory disease

What they're measuring

Oral Dryness

Timeframe: 2 week trial period

Trial details

NCT IDNCT04608773

SponsorJonas Johnson

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-11-15

Results submitted2023-11-15

View on ClinicalTrials.gov More Xerostomia trials