The leading cause of primary hyperparathyroidism (pHPT) is a solitary adenoma (89%). The treatment of pHPT is generally surgical removal of the overactive parathyroid gland(s). Since a solitary adenoma is the predominant cause, parathyroid surgery is preferably performed through a minimally invasive parathyroidectomy (MIP) in which only the suspected adenoma causing the pHPT is resected in a focused manner. To facilitate the performance of a MIP, accurate preoperative imaging is pivotal. This study aimed to analyze the diagnostic performance of 11C-choline PET/CT after prior negative or discordant first-line imaging in patients with pHPT undergoing parathyroid surgery with an optimized imaging protocol.
Age range
18 Years
Sex
ALL
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Sensitivity of 11C-choline PET/CT
Timeframe: Until 6 months after parathyroid surgery
Positive predictive value of 11C-choline PET/CT
Timeframe: Until 6 months after parathyroid surgery
Accuracy of 11C-choline PET/CT
Timeframe: Until 6 months after parathyroid surgery