CompletedNot Applicable

Effects of 650nm Low Energy Light on Human Retina and Choroid Microcirculation

China126 participantsStarted 2020-09-08

Plain-language summary

This project is a single-center, prospective, self-controlled clinical study. It intends to select patients with simple medium and low degree myopia as subjects, and apply 650nm low-energy red light irradiation to the retina to observe its effect on macular microcirculation.

Who can participate

Age range7 Years – 45 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Age from 7 to 17 years old or from 18 to 45 years old;
✓. Meet the diagnostic criteria for patients with simple low or moderate myopia, with diopter \< -6.0d and eye axis \< 26.0mm;
✓. Transparent refractive stroma, no other eye diseases except nearsightedness;
✓. Agree to participate in the clinical study and sign the informed consent.

Exclusion criteria

✕. Other ocular lesions, such as uveitis, retinal/choroidal vascular lesions, congenital ocular lesions, glaucoma, high myopia (ocular axis \> 26cm), degenerative retinal disease, optic neuropathy, etc.;
✕. Another eye with low vision
✕. Corneal edema/epithelial detachment, corneal opacity;
✕. Redness, pain, dry eye, photophobia, difficulty in opening eyes;
✕. Had a history of eye surgery in recent 3 months;
✕. Severe impairment of liver and kidney function and/or serious systemic diseases (such as cardiovascular, respiratory, digestive, nervous, endocrine, genitourinary, etc.);
✕. Women who are already pregnant, preparing for pregnancy during the study period and lactating;
✕. A history of substance abuse or alcohol abuse;

What they're measuring

retinal vascular density

Timeframe: 12 weeks

retinal vascular perfusion

Timeframe: 12 weeks

Choroid thickness

Timeframe: 12 weeks

Trial details

NCT IDNCT04604405

SponsorCentral South University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-10-09

View on ClinicalTrials.gov More Myopia trials

Who can participate

Age range7 Years – 45 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Age from 7 to 17 years old or from 18 to 45 years old;
✓. Meet the diagnostic criteria for patients with simple low or moderate myopia, with diopter \< -6.0d and eye axis \< 26.0mm;
✓. Transparent refractive stroma, no other eye diseases except nearsightedness;
✓. Agree to participate in the clinical study and sign the informed consent.

Exclusion criteria

✕. Other ocular lesions, such as uveitis, retinal/choroidal vascular lesions, congenital ocular lesions, glaucoma, high myopia (ocular axis \> 26cm), degenerative retinal disease, optic neuropathy, etc.;
✕. Another eye with low vision
✕. Corneal edema/epithelial detachment, corneal opacity;
✕. Redness, pain, dry eye, photophobia, difficulty in opening eyes;
✕. Had a history of eye surgery in recent 3 months;
✕. Severe impairment of liver and kidney function and/or serious systemic diseases (such as cardiovascular, respiratory, digestive, nervous, endocrine, genitourinary, etc.);
✕. Women who are already pregnant, preparing for pregnancy during the study period and lactating;
✕. A history of substance abuse or alcohol abuse;