Benzodiazepine sedative hypnotics are commonly used intravenous anesthetics in clinical practice. Remimazolam is a new benzodiazepine with the characteristics of rapid onset, short maintenance and recovery time, no accumulation, metabolism independent of liver and kidney function, and no serious side effects, which has a good prospect for clinical application. Now we will study the effects of remimazolam on EEG and postoperative cognitive function ，in order to further understand the clinical application of remimazolam.
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The average intraoperative power spectral density in the frontal alpha band
Timeframe: Preoperatively, During operation，End of operation
Changes in the score of MMSE
Timeframe: The outcome above should be measured the day before surgery and 1,2,3,5,7 days after surgery