UnknownNot Applicable

Develop a Multi-disciplinary Approach for a Personalized Prenatal Diagnostics and Care for Twin Pregnancies

Belgium, Canada, Germany1,200 participantsStarted 2020-12-21

Plain-language summary

Different screening modalities evaluation to develop algorithms to predict pregnancy complications in twin pregnancies, and evaluation of serologic response to BNT162b2 Pfeizer/BioNTech vaccination.

Who can participate

Age range18 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age \> 18 years; * Di-chorionic (DC)or Mono-chorionic (MC) twin pregnancies; * Both live fetuses at 11+0-13+6 weeks of gestation; * Informed and written consent Exclusion Criteria: * Monoamniotic twins * Triplet pregnancies that had undergone embryo reduction to twins or with one vanishing twin * Women who are unconscious or severely ill, those with learning difficulties, or serious mental illness; * Any other reason the clinical investigators think will prevent the potential participant from complying with the trial protocol.

What they're measuring

Adverse pregnancy outcome

Timeframe: through study completion, an average of 1 year

Adverse neonatal outcome

Timeframe: through study completion, an average of 2 year

Evaluation of serologic response to BNT162b2 Pfeizer/BioNTech vaccination.

Timeframe: through study completion, an average of 2 year including stored samples collected before vaccination was avaluable.

Trial details

NCT IDNCT04595214

SponsorAssaf-Harofeh Medical Center

Sponsor typeOTHER_GOV

Study typeOBSERVATIONAL

Primary completion2023-12-31

Contact for this trial

Ron Maymon, MD, PhD

+972-8-9779695 Ronm@shamir.gov.il

View on ClinicalTrials.gov More Prenatal Disorder trials