CompletedNot Applicable

Inducible Laryngeal Obstruction in Severe Asthma in Severe Asthma

Norway116 participantsStarted 2020-11-01

Plain-language summary

The first part will be a comparative cross-sectional study to identify the frequency of ILO and other comorbidites among participants with asthma compared to a group of reference subjects without asthma, matched for age- and gender and race. The second part will be a longitudinally observational study study following participants for one year after the cross-sectional study. The Maat-scores ILO-symptoms and asthma-outcomes longitudinally will be evaluated, .

Who can participate

Age range18 Years – 70 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with severe asthma (GINA 5) * Patients with mild-moderate well-treated asthma (GINA step 1-4) * Agroup of age- and gender matched control subjects without asthma also aged 18- 70. * The patients must have had a stable disease the last one month before performing the CLE-test Exclusion Criteria: * No have underlying neurologic disease. * No known cancer in the lung-head-neck * No known vocal cord pathology. * No history of life-threatening asthma required hospitalization.

What they're measuring

Prevalence of ILO in the participants

Timeframe: One year

Changes in continues during exercise (CLE-)-test score

Timeframe: One year

Trial details

NCT IDNCT04593394

SponsorHaukeland University Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-10-01

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