CompletedNot Applicable

Genicular Artery Embolization to Reduce Pain Associated With Unilateral Mild to Moderate Osteoarthritis

United States5 participantsStarted 2021-09-22

Plain-language summary

The goal of this study is to perform a feasibility study to show the effectiveness of the genicular artery embolization procedure in reducing bilateral or unilateral osteoarthritic knee pain at 12 months as measured by WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) score, Knee Injury and Osteoarthritis Outcome (KOOS) score, and Oswestry Disability Index.

Who can participate

Age range40 Years – 80 Years

SexALL

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Inclusion criteria

✓. Patients aged 40-80
✓. Bilateral or Unilateral knee pain attributed to osteoarthritis
✓. Grade 1-3 Osteoarthritis as diagnosed on standing weight-bearing knee radiographs per the Kellen-Lawrence Grading scale
✓. Knee pain \>6 months refractory to conservative medical management (NSAIDs, paracetamol, intra-articular injections, physiotherapy/exercise, weight loss, etc.)

Exclusion criteria

✕. Active malignancy
✕. Active infection of the affected knee
✕. Platelets \<50,000
✕. INR \>1.8 (unless on anticoagulation that can be reversed)
✕. Corticosteroid injection of the affected knee within 3 months
✕. Rheumatoid arthritis or other seronegative arthropathy
✕. Previous surgery (excluding arthroscopy) of the affected knee
✕. Grade 4 per Kellgren-Lawrence Grading Scale of the affected knee

What they're measuring

WOMAC Scale

Timeframe: 12 Months

KOOS Scale

Timeframe: 12 Months

Oswestry Disability Index

Timeframe: 12 Months

Trial details

NCT IDNCT04592562

SponsorUniversity of Chicago

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-05-28

View on ClinicalTrials.gov More Knee Osteoarthritis trials