CompletedNot Applicable

FIBRotic Interstitial Lung Disease and Nocturnal OXygen

United Kingdom102 participantsStarted 2018-12-17

Plain-language summary

Home sleep studies - which allow the measurement of breathing while the person sleeps - will be performed on patients with fibrotic interstitial lung disease attending two of the UK's largest respiratory medicine services.The study will investigate at how symptoms, and breathing and exercise tests differ between these two groups after 12 months of study.

Who can participate

Age range

20 Years – 90 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * MDT diagnosis of fibrotic interstitial lung disease including but not limited to idiopathic pulmonary fibrosis (IPF), non-specific interstitial pneumonitis (NSIP), chronic hypersensitivity pneumonitis (CHP), fibrotic organising pneumonia and unclassifiable fibrotic lung disease. * Competent to provide written consent in English Exclusion Criteria: * Presence of an underlying connective tissue disease * Daytime/resting hypoxaemia with pO2 \<8.0 * Other indication for oxygen therapy * 3% ODI \>15 events/hour studied or established on CPAP * Predominant emphysema on CT * Inability to provide informed consent or complete health-related quality of life questionnaires in English * Current participation in a research project which might alter lung function or sleep study results

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Quality of life measured by King's Brief Interstitial Lung Disease Questionnaire (K-BILD)

Timeframe: 0 months,12 months

Trial details

NCT IDNCT04586946

SponsorGuy's and St Thomas' NHS Foundation Trust

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2021-05-30

View on ClinicalTrials.gov More Idiopathic Pulmonary Fibrosis trials