CompletedNot Applicable

Comparison Between Two Revascularization Strategies in MVD Patients With Uncomplicated ST-elevation MI

Romania100 participantsStarted 2020-07-01

Plain-language summary

The study aimed to compare major adverse cardiac and cerebrovascular events(MACCE) and mortality at one year between two strategies: complete revascularization including non-culprit lesions percutaneous coronary intervention(PCI) during primary PCI(PPCI) versus complete revascularisation during the same hospital admission in multi-vascular coronary artery disease(MVD) patients presenting with ST-elevation myocardial infarction(STEMI) uncomplicated by cardiogenic shock.

Who can participate

Age range18 Years – 90 Years

SexALL

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Inclusion criteria

✓. Men and women with successful PCI (preferably using a drug-eluting stent) to the culprit lesion for STEMI ( PCI for STEMI should be primary PCI in the first 12 hours after symptom onset) and complete revascularization of non-culprit lesions during the index PPCI procedure or during a different procedure performed before index hospital discharge.
✓. Multi-vessel disease defined as at least 1 additional non-infarct related coronary artery lesion that is at least 2.5 mm in diameter that has not been stented as part of the primary PCI and that is amenable to successful treatment with PCI and has:
✓. Age between 18 and 90 years
✓. Written informed consent could be obtained from all the patients

Exclusion criteria

✕. Rescue PCI for failed fibrinolysis or a combination strategy where PCI is performed routinely 3-12 hours after fibrinolysis
✕. Cardiogenic shock
✕. Non-cardiovascular known co-morbidity reducing life expectancy to \< 2 years
✕. Any factor precluding 1year follow-up
✕. Prior Coronary Artery Bypass Graft (CABG) Surgery
✕. A different operator from the previously designated
✕. Unable to provide consent for any other reason

What they're measuring

one year all-cause mortality

Timeframe: one year

MACCE at one year

Timeframe: one year

Trial details

NCT IDNCT04582175

SponsorUniversity of Oradea

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2020-09-01

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