Effects of Visnadin, Ethyl Ximeninate, Coleus Barbatus and Millet in Emulgel on Sexual Function in Postmenopausal Women

Inclusion Criteria: * Women age 45-65 years old * BMI 19-29 kg/m2 * Menopause or removal of both ovaries more than 1 year * Has moderate to severe vulvovaginal atrophic at least 1 symptom * Has sign of vulvovaginal atrophy * Vaginal pH ≥ 5 * Has sexual intercourse at least 1 time/month Exclusion Criteria: * Hormonal use within 3 months * Use vaginal estrogen/ moisturizer within 3 months * Use aromatase inhibitor/tamoxifen within 3 months * Has vaginal bleeding within 6 months * Acute or chronic urinary tract infection * History of radiation therapy at vulvovaginal and pelvic area * History of Diabetes mellitus or Cardiovascular disease * History of neurosis or psychosis * History of vulvovaginal cancer * History of smoking more than 20 cigarettes/day * History of alcoholic drink/ drug abuse * History of visnadin, ethyl ximeninate, coleus barbatus and millet allergy * Has disease of vulva