CompletedNot Applicable

Clinical Comparison of Treatment Strategies in AmpC Beta-lactamase Producing Enterobacterales in a Swiss Tertiary Care Hospital

Switzerland270 participantsStarted 2020-12-14

Plain-language summary

This study is to investigate the recent epidemiological trends and the treatment outcome in terms of the length of hospital stay, the relevant renal and neurological side effects, risk factors for developing these side effects, the selection of more resistant pathogens under therapy as well as the incidence of Clostridium difficile infections under treatment.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. In a blood culture (any ward)
. In a clinical sample of the lower respiratory tract (only intensive care unit)

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

descriptive analyses of demographic data in patients with detection of AmpC beta-lactamase producing Enterobacterales

Timeframe: single time-point at baseline

descriptive analyses of clinical data in patients with detection of AmpC beta-lactamase producing Enterobacterales

Timeframe: single time-point at baseline

descriptive analyses of treatment data in patients with detection of AmpC beta-lactamase producing Enterobacterales

Timeframe: single time-point at baseline

descriptive analyses of microbiological data in patients with detection of AmpC beta-lactamase producing Enterobacterales

Timeframe: single time-point at baseline

Trial details

NCT IDNCT04577989

SponsorUniversity Hospital, Basel, Switzerland

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-12-19

View on ClinicalTrials.gov More Infection With AmpC Beta-lactamase Producing Enterobacterales trials

Plain-language summary

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. In a blood culture (any ward)
. In a clinical sample of the lower respiratory tract (only intensive care unit)

What they're measuring

descriptive analyses of demographic data in patients with detection of AmpC beta-lactamase producing Enterobacterales

Timeframe: single time-point at baseline

descriptive analyses of clinical data in patients with detection of AmpC beta-lactamase producing Enterobacterales

Timeframe: single time-point at baseline

descriptive analyses of treatment data in patients with detection of AmpC beta-lactamase producing Enterobacterales

Timeframe: single time-point at baseline

descriptive analyses of microbiological data in patients with detection of AmpC beta-lactamase producing Enterobacterales

Timeframe: single time-point at baseline