CompletedNot Applicable

Age-Related Changes and Cycloplegia-Induced Differences in the Human Crystalline Lens

China129 participantsStarted 2019-04-01

Plain-language summary

The ocular biometric parameters of the human crystalline lens including anterior chamber depth (ACD), lens thickness (LT), radii of curvature of anterior and posterior lens (ALR and PLR), lens equatorial diameter (LED), and lens vault (LV), automatically quantified by the CASIA2 (SS-OCT; Tomey, Nagoya, Japan). Images of iridocorneal angle were obtained using CASIA2 and the Schlemm' s canal (SC) and trabecular meshwork (TM) were quantified manually. Both cycloplegia and non-cycloplegia images were obtained.

Who can participate

Age range6 Years – 86 Years

SexALL

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Inclusion Criteria: Healthy individuals aged between 6 and 90 years, without history of ocular disease (except age-related cataract and/or myopia) Must be able to cooperate examination Exclusion Criteria: ocular diseases other than cataracts history of eye surgeries or injuries shallow anterior chamber with a risk of angle closure

What they're measuring

Paired Comparison Before and After Cycloplegia

Timeframe: 2020.2.3

Evaluated the effect of age on the TM/SC morphologies

Timeframe: 2020.2.3

Trial details

NCT IDNCT04576884

SponsorWenzhou Medical University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2019-05-31

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