CompletedNot Applicable

The EPIVER Randomized Controlled Trial

Russia104 participantsStarted 2020-12-30

Plain-language summary

The trial aims to estimate the efficacy and safety of the intracoronary administration of adrenalin, verapamil, as well as their combination compared to standard treatment in patients with STEMI and refractory coronary no-reflow despite conventional treatment during percutaneous coronary intervention (PPCI)

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * patients with ST-elevation myocardial infarction * Infarct-related artery TIMI flow grade 0-2 during the interventional procedure after the initial opening of the vessel. * Written the informed consent to participate in research Exclusion Criteria: * Unable to undergo or contra-indications for MRI or SPECT

What they're measuring

Mortality

Timeframe: month 1

New onset or worsening acute heart failure

Timeframe: month 1

Trial details

NCT IDNCT04573751

SponsorTomsk National Research Medical Center of the Russian Academy of Sciences

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-01-31

View on ClinicalTrials.gov More ST Elevation Myocardial Infarction trials