UnknownNot Applicable

Benefit of ESP Peri Operative Analgesia for Live Liver Donor Transplantation

Vietnam24 participantsStarted 2020-11-01

Plain-language summary

Liver donors have a significant risk to develop persistent and chronic pain around 20 to 30% affecting social and professional life (17%) up to 1 year after the surgery. To donate a part of liver is a beautiful gift reason why the pain relief must be improved. Meta-analysis showed that the best prevention against post operative chronic pain are the techniques blocking the pain signal (regional anaesthesia) Patients after liver donation are still in pain even in 2020 with the best multimodal analgesia medications. Erector sinae Plane Block (ESP) ESP will block the signal and improve the pain relief we hope to demonstrate that it will reduce the risk to develop post operative chronic pain and improve the quality of recovery and the quality of life after liver donation

Who can participate

Age range18 Years – 60 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * age more than 18 and less than 61 * Be volunteer to donate liver * agree to participate to study and consent signed * Risk of americain society of anesthesiologists score ASA from 1 to 5 score ASA must be 1 only Exclusion Criteria: * Use of chronic opioid before the surgery * A diagnosis of chronic pain condition * Contra indication to perform ESP catheter * allergy to local anesthestics * Depression or psychiatric diagnosis

What they're measuring

quality of pain relief at rest

Timeframe: from day 0 = day of surgery to day 180

quality of pain relief at mouvement

Timeframe: from day 0 = day of surgery to day 180

Trial details

NCT IDNCT04570969

SponsorVinmec Healthcare System

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-11-30

View on ClinicalTrials.gov More Liver Transplant Disorder trials