CompletedNot Applicable

Acute Effects of TCIG vs ECIG in PLWH

United States37 participantsStarted 2020-10-01

Plain-language summary

Randomized controlled trial of acute use of electronic cigarette or tobacco cigarette on parameters of ventricular repolarization and inflammation/oxidative stress.

Who can participate

Age range21 Years – 45 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Chronic (\> 1year) TCIG smoker HIV positive Stable ART Viral count non-detectable CD4 \>500 Exclusion Criteria: Known major illness (heart disease, diabetes, lung or liver disease) Daily recreational drug use, including cannabis \>2 alcoholic drinks per day Obesity (\>30 kg/m2) Recent (\<3 months) infection

What they're measuring

Tpe

Timeframe: Change in Tpe 5 minutes after cigarette use

Tpe/QT

Timeframe: Change in Tpe/QT after cigarette use

Tpe/QTc

Timeframe: Change in Tpe/QTc after cigarette use

Total Cellular Reactive Oxygen Stress

Timeframe: within 4 hours of cigarette use

Trial details

NCT IDNCT04568395

SponsorUniversity of California, Los Angeles

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-05-08

View on ClinicalTrials.gov More E Cigarette Use trials