CompletedNot Applicable

Streptococcus Mutans Cariogenicity by Real-time PCR in High Caries Risk Patients

Egypt37 participantsStarted 2021-01-01

Plain-language summary

In patients with high caries risk, will the use of cinnamon extract or chlorohexidine based mouthwashes have an effect on the percentage of recovery and cariogenicity of Streptococcus mutans (SM) detected by real-time Polymerase Chain Reaction (PCR) over one month follow up

Who can participate

Age range20 Years – 50 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adults will be recruited in this study, all the volunteers participated in this experiment will be healthy looking with free medical history. * Age range 20-50 years * High caries risk patients according to ADA caries risk assessment model. * High plaque index (\>score 2) * Non-smoking patients. * Patients with normal salivary rate (0.3-0.4 ml/min). Exclusion Criteria: * Patients with a compromised medical history. * Participants with low caries risk. * Patients with severe or active periodontal disease. * Participants with a history of allergy to any of the drugs or chemicals used in the study. * Patients on any antibiotics during the past month * Smoking patients. * Patients with abnormal salivary rate. * Pregnant female patients

What they're measuring

Total bacterial count

Timeframe: 1 month

Trial details

NCT IDNCT04566120

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-12-01

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