Streptococcus Mutans Pathogenicity by Real-time Polymerase Chain Reaction (PCR) in High Caries Ri… (NCT04565912) | Clinical Trial Compass
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Streptococcus Mutans Pathogenicity by Real-time Polymerase Chain Reaction (PCR) in High Caries Risk Patients
37 participantsStarted 2021-07-06
Plain-language summary
In patients with high caries risk, will the use of sage extract or chlorohexidine based mouthwashes have an effect on the percentage recovery of Streptococcus Mutans (SM) and its pathogenicity detected by Real-Time Polymerase Chain Reaction (PCR) over one month follow up
Who can participate
Age range20 Years – 50 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* patients will be recruited in this study, all volunteers participated will be medically free Age range 20-50
* Patients with high caries risk assessment according to ADA caries risk assessment model High plaque index (\>score 2 )
* Non smoking patients
* Patients with normal salivary rate ( 0.3-0.4 ml/min)
* Not under antibiotic therapy either time of the study or up to the last month before the begging of the study
* Male or female patients.
Exclusion Criteria:
* patients with a compromised medical history.
* Patients with low caries risk assessment according to ADA caries risk assessment model.
* Patients with sever or active periodontal disease.
* Patients with a history of allergy to any of drugs or chemicals used in this study.
* Smoking patients
* Patients with abnormal salivary rate
* Pregnant female patients.