TerminatedNot Applicable

Breath Metabolomics in the Laboring Parturient

Stopped: Staffing and equipment complications have paused further enrollment until resolved

United States53 participantsStarted 2020-11-11

Plain-language summary

This is primarily a feasibility study to determine whether quantitative measurement of volatile organic compounds (VOCs) in the breath of parturients undergoing labor is possible. Aim A: To determine baseline values of breath metabolites and volatile organic compounds (VOCs) in the breath for term pregnant women. Aim B: To gather preliminary data to determine breath metabolite and volatile organic compound (VOCs) signature change during labor and delivery. Aim C: Compare the breath metabolite and volatile organic compound (VOCs) signature women undergoing induction compared to spontaneous vaginal deliveries.

Who can participate

Age range18 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Otherwise healthy nulliparous women with singleton term (37-41 weeks) pregnant at least 18 years of age. * Presenting for labor (induction of labor and spontaneous labor) at LPHC. Exclusion Criteria: * Participants unable to or refuse to give informed consent * Participants that do not understand English or are hearing impaired * Medical History: Chronic disease (HTN, diabetes, asthma) * Obstetric History during this pregnancy: gestational diabetes, gestational hypertension, pre-eclampsia, Eclampsia * Multiple gestation * Any significant fetal anomalies * Morbid obesity (BMI\>50)

What they're measuring

Profile of volatile organic compounds of the breath

Timeframe: Up to 24 hours

Trial details

NCT IDNCT04564196

SponsorStanford University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-06-06

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