Efficacy and Safety of Bolus Comparing With Continuous Drip of 3% NaCl in Patients With Severe Symptomatic Hyponatremia.

Inclusion Criteria: * Patients in Rajavithi Hospital * Age from 18 years * Plasma Na \< 125 mmol/l with glucose-corrected * Severe symptomatic hyponatremia (Vomitting ,Coma ,Somnolence) Exclusion Criteria: * Systolic BP \< 90 mmHg Or MAP\< 70 mmHg * Pregnancy or Lactation * Congestive Heart Failure or Volume overload * Lung congestionfrom CXR * Chronic renal failure patients with edema * Cirrhosis patients with edema * Patients with coronary artery disease * Patients with brain injuries * Deny consent