Older women with cardiovascular disease (CVD) are at greater risk for memory loss, an important public health issue due to the negative effects to quality of life and health care costs. This research will be the first to examine the independent and combined effects of a lifestyle physical activity intervention and cognitive training on memory performance and memory-related serum biomarkers in this vulnerable population. The investigators will incorporate a practical lifestyle approach that can be delivered in the home and community settings to prevent or delay memory loss in older women with CVD.
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Change in East Boston Memory Test Scores From Baseline to 24 Weeks, 48 Weeks, and 72 Weeks
Timeframe: Baseline, and 24 weeks, 48 weeks, and 72 weeks post-baseline
Change in Category Fluency Test Scores From Baseline to 24 Weeks, 48 Weeks, and 72 Weeks
Timeframe: Baseline, and 24 weeks, 48 weeks, and 72 weeks post-baseline
Change in Digit Span Forwards and Backwards Test Scores From Baseline to 24 Weeks, 48 Weeks, and 72 Weeks
Timeframe: Baseline, and 24 weeks, 48 weeks, and 72 weeks post-baseline
Change in Oral Trails A/B Tests Scores From Baseline to 24 Weeks, 48 Weeks, and 72 Weeks
Timeframe: Baseline, and 24 weeks, 48 weeks, and 72 weeks post-baseline
Change in Digit Ordering Tests Scores From Baseline to 24 Weeks, 48 Weeks, and 72 Weeks
Timeframe: Baseline, and 24 weeks, 48 weeks, and 72 weeks post-baseline