UnknownNot Applicable

PTSD, AUD, and Interpersonal Conflict: Within-person Associations

United States250 participantsStarted 2020-12-04

Plain-language summary

The present study seeks to increase understanding of Alcohol Use Disorder (AUD) and Posttraumatic Stress Disorder (PTSD) among veterans, an important public health concern. We will study the effects of regulatory deficits and sleep disturbance on the dynamic course of PTSD and AUD. The study will investigate whether a short, computerized training in the laboratory will alter maladaptive response biases and reduce associations between sleep disturbance, affect and behavioral dysregulation, AUD symptoms, and PTSD symptoms in the real world.

Who can participate

Age range18 Years – 60 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * OIF/OEF/OND veterans * At risk for PTSD (i.e., PCL-5 ≥33) and/or AUD (i.e., AUDIT ≥ 7 (women) ≥ 8 (men)) Exclusion Criteria: * Psychosis or severe Alcohol Use Disorder that contraindicates participation (based on interview) * Active suicidal or homicidal ideation that contraindicates participation (based on interview) * \[exclusion criteria removed 6/2022\] - Severe risk for sleep apnea (a positive score in three categories of the Berlin Questionnaire), or reported treatment for sleep apnea

What they're measuring

Rate of Alcohol Use Disorder Symptoms

Timeframe: 2 years

Rate of PTSD Symptoms

Timeframe: 2 years

Trial details

NCT IDNCT04552782

SponsorUniversity of South Dakota

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-04-30

Contact for this trial

Jeffrey S Simons, PhD

605-658-3710 jeffrey.simons@usd.edu

View on ClinicalTrials.gov More Stress Disorders, Post-Traumatic trials