Comparison of Dimensional Changes After Tooth Extractions Between Xenograft and Allograft (NCT04550689) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Comparison of Dimensional Changes After Tooth Extractions Between Xenograft and Allograft
United States12 participantsStarted 2020-10-01
Plain-language summary
To compare dimensional changes in extraction socket of single rooted teeth, 6 months post extraction, when grafted with xenograft versus allograft.
Who can participate
Age range
21 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Males or females ≥ 21 years of age
. Able to provide informed consent
. Good general oral health (no active periodontal disease, absence of hopeless teeth, absence of active caries, absence of acute infections)
. Single rooted non molar teeth needing extraction for miscellaneous reasons (since histological analysis is being done, it is essential to harvest bone core biopsies without inclusion of native bone16)
. Presence of natural teeth adjacent to the tooth planned for extraction
. Absence of acute signs of infection such as pus discharge, fistulous tract and / or abscess in relation to tooth being extracted
. Dehiscence type defects of the sockets limited to 2/3rd length of the root
Exclusion criteria
. Conditions and circumstances as evaluated by investigator that would prevent completion of study participation
. Conditions requiring chronic routine use of antibiotics or steroids
. History of leukocyte dysfunction or deficiencies, bleeding disorders, neoplastic disease requiring radiation or chemotherapy, metabolic bone disorder, uncontrolled endocrine disorders, HIV infections
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Horizontal and vertical dimensional changes noted on Cone Beam Computed Tomography