Intensive Care Unit (ICU) patients are known to lose muscle mass and function for many reasons, ranging from prolonged immobilization, to the effects of ICU treatments such as mechanical ventilation (MV), to the critical illness itself. Ultrasonography (US) is widely used in the ICU setting and has greatly evolved in the last decades, since it allows the non-invasive assessment of different structures, using radiation-free and user-friendly technology; its application for the assessment or the skeletal muscle is a promising tool and might help detecting muscle changes and thus several dysfunctions during early stages of ICU stay. By using skeletal muscle ultrasound at both diaphragm and peripheral levels, the overall aim of this study is to improve knowledge in the early detection of muscle dysfunction and weakness , and their relationship with mechanical ventilation weaning and muscle strength, in critically ill patients suffering from septic shock.
Age range
18 Years
Sex
ALL
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Association between SWE assessment and other muscle ultrasound markers.
Timeframe: Baseline (at 24 hours after ICU admission)
Association between SWE assessment and other muscle ultrasound markers.
Timeframe: Day 2, after ICU admission
Association between SWE assessment and other muscle ultrasound markers.
Timeframe: Day 3, after ICU admission
Association between SWE assessment and other muscle ultrasound markers.
Timeframe: Day 4, after ICU admission
Association between SWE assessment and other muscle ultrasound markers.
Timeframe: Day 5, after ICU admission
Association between SWE assessment and other muscle ultrasound markers.
Timeframe: Extubation day, approximately 7 days
Association between SWE assessment and other muscle ultrasound markers.
Timeframe: Weekly (1x/week), counting from day 6 of ICU stay until ICU discharge (approximately 10 days)
Association between SWE assessment and other muscle ultrasound markers.
Timeframe: ICU discharge, approximately 10 days