Nutritional Interventions in Peritoneal Dialysis Patients with Hypoalbuminemia (NCT04546958) | Clinical Trial Compass
CompletedNot Applicable
Nutritional Interventions in Peritoneal Dialysis Patients with Hypoalbuminemia
Taiwan33 participantsStarted 2020-10-02
Plain-language summary
Inadequate dietary protein intake is well-known cause of hypoalbuminemia in dialysis population. Protein loss into dialysate and increased catabolic state due to uremic milieu or inflammation worsened hypoalbuminemia, hence high protein diet is recommended in patients on peritoneal dialysis (PD). The recommendations from K/DOQI clinical practice guidelines for the amount of daily protein intake is based on expert opinion and the optimal daily protein intake in PD patients is not known. The investigators hypothesize that higher dietary protein intake has a greater beneficial effect on nutritional status in hypoalbuminemic PD patients. In particular, 1.5 g/kg protein intake provides a better beneficial effect than 1.2 g/kg protein intake.
Who can participate
Age range20 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Aged greater than or equal to 20 years
✓. Having end-stage kidney disease and having undergone maintenance PD for more than three months
✓. Having adequate dialysis (weekly Kt/V greater than or equal to 1.7)
✓. Serum albumin levels lower than 4.0 g/dL, measured by bromocresol green assay
Exclusion criteria
✕. Untreated fluid overload
✕. Uncorrected metabolic acidosis
✕. Having active infection or inflammation
✕. Hospitalization within the past 4 weeks
✕. Having gastrointestinal bleeding
✕. those who cannot cooperate with the dietary record
✕. those who have poor adherence to whey protein consumption