Energy Expenditure and Quality of Life in Epilepsy

Inclusion Criteria (in person participation): * aged 18-45 * Diagnosis of epilepsy * Experience an average of 2 or more seizures per month during the 3 months prior to study * Plan to start oral ketogenic diet therapy (e.g. with the modified Atkins diet) * Have low average or higher cognitive/intellectual function and are able to complete self-report questionnaires Inclusion Criteria for Remote Participation: * over 18 years of age (no age limit) * Diagnosis of epilepsy * Experience an average of 2 or more seizures per month during the 3 months prior to study * Plan to start oral ketogenic diet therapy (e.g. with the modified Atkins diet) * Have low average or higher cognitive/intellectual function and are able to complete self-report questionnaires Exclusion Criteria: * Participants who report being claustrophobic * Presence of edema, conditions or persistent side effects of medication use (e.g. vomiting, diarrhea, excessive sweating, and burns) that could cause alterations in the body hydration and consequently, be a bias in energy metabolism variables * Currently using medications that may cause metabolic and/or absorptive alterations (e.g. diuretics, amphetamines, lipase inhibitors, corticosteroids, etc.) * Unstable metabolic condition (e.g. persistent sodium \<130 or glucose \<50) * Liver, kidney, or pancreatic disease * Hypercholesterolemia (cholesterol \> 300mg/dL) * Currently pregnant or planning on becoming pregnant * Fatty acid oxidation disorder or pyruvate ca…