Effects of Testosterone Plus Dutasteride or Placebo on Muscle Strength, Body Composition and Metabolism in Transmen

Inclusion Criteria: * Healthy transmen * Previous bilateral gonadectomy during sex reassigning surgery * Body Mass Index (BMI) between 20 and 29 kg/m²; (body weight in kilograms divided by body height in meters squared) * Clinical examination without pathological findings relevant to the study * No concomitant use of drugs known to affect the hypothalamic-pituitary-ovarian axis * Written Consent Form * High probability of a good compliance and termination of the study Exclusion Criteria: * Participation in another clinical trial within the 30 days preceding the first administration * Simultaneous participation in another clinical trial * Subjects institutionalized or imprisoned by order of the court * Subject who compete in sports * Subjects reporting desire to perform regular physical exercises for the duration of the study * Serious organic or psychic disease suspected from history and/or clinical examination * Diseases (especially tumors) that might represent an actual contraindication for testosterone * Past or present history of thrombotic or embolic diseases * Arterial hypertension * Diabetes mellitus * Acute or chronic hepatic diseases * Manifest renal diseases with renal dysfunction * Severe internal diseases * Biochemical and/or hematological laboratory values beyond normal ranges unless the Investigator confirms that the deviations are of no clinical relevance * Any indication of chronic use of drugs, alcohol, opiates or recreational drugs * Use of any drug known…