UnknownNot Applicable

Endovascular Graft Anchoring Different Regions of Ascending Aorta in the Treatment of Ascending Aortic Dissection

200 participantsStarted 2020-10-01

Plain-language summary

Aortic dissection is a deadly and dangerous disease. About 28% of patients with ascending aortic dissection can't tolerate open surgical trauma caused by thoracotomy and cardiopulmonary bypass, and the prognosis is poor. Minimally invasive endovascular treatment has been applied in the treatment of descending aortic dissection. However, due to the special anatomical structure and high speed /pressure blood flow, the treatment of ascending aorta dissection has become an international difficulty.

Who can participate

Age range

18 Years – 100 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Aortic dissection diagnosed by CTA; * With indications for endovascular treatment * The luminal graft anchor is required to be located in the ascending aorta. Exclusion Criteria: * Import difficult, such as external iliac artery diameter is less than 6 mm bilateral iliac, artery stenosis distortions; * Patients with severe comorbidities, such as severe myocardial insufficient blood supply, heart failure, arrhythmia, severe renal dysfunction, and severe blood coagulation dysfunction; * Patients with malignant tumor, or other serious illness, life expectancy of less than 1 year； * Puncture local infection and high fever;⑤ within 1 month of the large area; * Contrast media in patients with cerebrovascular accident or digestive tract hemorrhage patients with allergies; * Aortic ulcer or aortic wall hematoma and other atypical dissection.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

success of operation

Timeframe: before December 2022

Trial details

NCT IDNCT04544579

SponsorChinese Medical Association

Sponsor typeNETWORK

Study typeOBSERVATIONAL

Primary completion2022-09-01

Contact for this trial

Zaiping Jing, professor

02131161670 xueguanky@163.com

View on ClinicalTrials.gov More Ascending Aortic Dissection trials