FAST (Focused Abbreviated Screening Technique)-MRI Study (NCT04539717) | Clinical Trial Compass
By InvitationNot Applicable
FAST (Focused Abbreviated Screening Technique)-MRI Study
United States820 participantsStarted 2020-08-17
Plain-language summary
The purpose of this study is to compare the diagnostic value of a reconstructed abbreviated Magnetic Resonance Imaging (MRI) from a full clinical exam, compared to ultrasound (US) for screening of liver cancer. Blood markers will be evaluated to determine their correlation to imaging. This study will help to determine whether abbreviated MRI is superior to ultrasound for diagnosis of liver cancer.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria
* Liver cirrhosis of any etiology.
* 18 years of age and older.
* Enrolled in screening/surveillance program for HCC.
* Clinically indicated imaging-based screening for HCC.
* Willing and able to complete all study procedures within specified time windows.
* Patient is able to give informed consent for this study.
Exclusion Criteria
* Contra-indications to MRI.
* Age less than 18 years.
* Patients with chronic renal failure or inability to tolerate contrast.
* Inability to undergo MRI due to lack of insurance coverage.
* Prior negative screening exam less than 5 months prior to enrollment.
* Prior hepatic resection.
* Post liver transplantation.
* Previously treated HCC or other liver neoplasm.
* Any other condition or factor that in judgment of study investigator may interfere with study completion.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Presence of HCC
Timeframe: Within 6 months after initial index imaging (MRI & US)