CompletedNot Applicable

Evaluation of the Sevoflurane Consumption During General Anesthesia When Using the MemsorbTM Membrane

Canada50 participantsStarted 2021-05-04

Plain-language summary

The study aims at determining whether replacing the classical chemical absorber Dräegersorb 800+ on Dräeger Perseus A500 machines (Dräeger, Lübeck, Germany) by the new membrane technology-based product (Memsorb™, DMF Medical Inc., Halifax, NS, Canada) with the help of high-quality monitoring (BIS and NOL) and high-end ventilators (Dräeger Perseus A500 machines; Dräeger, Lübeck, Germany) that allow minimal fresh gas flow, will significantly decrease the use of sevoflurane and its related atmospheric pollution.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * ASA 1-3, * Laparoscopic general, gynecological or urologic surgery requiring general anesthesia without additional regional anesthesia technique, * Fully consented, * BMI \< 40, * Age \> 18. Exclusion Criteria: * Allergy or contra-indication to any drug used in the study protocol, * History of unstable coronary artery disease, * Serious cardiac arrhythmia (including atrial fibrillation), * History of substance abuse in the last 2 months prior to surgery, * Chronic use of psychotropic and/or opioid drugs (still existing within the last month prior to surgery, * History of psychiatric diseases, * History of refractory PONV in previous surgery, * Allergy to any drug used in the study protocol, * Non-scheduled surgery, * Refusal of the patient for participation in the study.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

To show a significant decrease of at least 25% of the sevoflurane consumption

Timeframe: Intraoperative

Trial details

NCT IDNCT04539405

SponsorCiusss de L'Est de l'Île de Montréal

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-02-18

View on ClinicalTrials.gov More Laparoscopic General, Gynecological and Urologic Surgeries trials