CompletedPhase 4

Copd Exacerbation and Pulmonary Hypertension Trial

Denmark250 participantsStarted 2020-02-01

Plain-language summary

This trial will investigate whether patiens admitted with an acute exacerbation of chronic obstructive lung disease and pulmonary hypertension will benefit from a targeted pharmacological treatment.

Who can participate

Age range40 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * COPD verified by specialist and spirometry * Admitted with the diagnosis "acute exacerbation of COPD" * TR-gradient ≥40 mmHg verified by specialist and echocardiography * Informed consent Exclusion Criteria: * Known pulmonal hypertension * Known heart disease which affects the pump function of the heart * Men \<40 years * Women \<55 years * Not-menopauseal women \<55 years (Menopause is defined as no menstruation within 12 months.) * Severe mental illness which significantly complicates cooperation * Severe language difficulties which significantly complicates cooperation * known allergy to Sildenafil * Sildenafil consumption ≥50 mg / week due to other indications

What they're measuring

Time alive and out of hospital

Timeframe: 365 days

Trial details

NCT IDNCT04538976

SponsorChronic Obstructive Pulmonary Disease Trial Network, Denmark

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-03-15

View on ClinicalTrials.gov More Acute Exacerbation of COPD trials