Impact of CKD on Children and Their Families

Inclusion Criteria: * Age from eight to twelve years. * Both genders. * Diagnosed with ESRD (stage 5) based on the glomerular filtration rate (GFR \< 15 mL/minute/1.73 m2). * Able to understand and follow instructions during assessment procedures. * Willing to participate in the study and attend the assessment procedures. Exclusion Criteria: Children of the following criteria will be excluded from the study: * Cardiopulmonary disorders * Uncontrolled hypertension * Unstable angina * Severe uncontrolled diabetes * Neurological or cognitive disorders with functional deficits * Significant cerebral or peripheral vascular disease.