Cardiovascular Responses to Heat Waves in the Elderly (NCT04538144) | Clinical Trial Compass
CompletedNot Applicable
Cardiovascular Responses to Heat Waves in the Elderly
United States59 participantsStarted 2021-01-19
Plain-language summary
The purpose of this study is to assess the cardiovascular responses of the elderly to heat wave conditions
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Healthy male and female individuals
* 18-35 years or 65+ years of age
* Free of any underlying moderate to serious medical conditions
Exclusion Criteria:
* Known heart disease; other chronic medical conditions requiring regular medical therapy including cancer, diabetes, neurological diseases, uncontrolled hypertension, and uncontrolled hypercholesterolemia.
* Taking of any medications (such as beta blockers and non-dihydropyridine calcium channel blockers) that have known influences on either cardiac function or sweating responses.
* Abnormalities detected on routine screening.
* Individuals who participate in a structured aerobic exercise training program at moderate to high intensities.
* Current smokers, as well as individuals who regularly smoked within the past 3 years.
* Body mass index of greater than 30 kg/m\^2
* Pregnant individuals
What they're measuring
1
Change in Core Body Temperature
Timeframe: Prior to and after the 3-hour simulated heat wave exposure.
2
Change in Peak Mitral Annular Systolic Velocity (S')
Timeframe: Prior to, during, and after each simulated heat wave exposure; approximately 20 min each
Trial details
NCT IDNCT04538144
SponsorUniversity of Texas Southwestern Medical Center