Nicotine's Potential Abuse With Menthol

Inclusion Criteria: * 1\) Female and male smokers, aged 21 to 35 years, who have been smoking tobacco cigarettes for at least a year; * 2\) smoke ≥ 5 and less than 20 cigarettes per day; * 3\) urine cotinine levels \> 100 ng/mL consistent with nicotine intake of an active smoker * 4\) not seeking treatment at the time of the study for nicotine dependence; * 5\) in good health as verified by medical history, screening examination, and screening laboratory tests; * 6\) for women, not pregnant as determined by pregnancy screening, nor breast feeding, and using acceptable birth control methods. Exclusion Criteria: * 1\) history of major medical or psychiatric disorders that the physician investigator deems as contraindicated for the subject to be in the study; * 2\) regular use of psychotropic medication (antidepressants, antipsychotics, or anxiolytics); * 3\) current alcohol or substance dependence for any other recreational or prescription drugs other than nicotine; * 4\) use of e-cigarettes more than 10 days in the past 30 days; * 5\) urine drug screening indicating recent illicit drugs use (with the exception of marijuana).