Due to the age associated sarcopenia and reduced cardiovascular fitness, frail older adults experience significant decrease in physical function which comprises of mobility, endurance, muscle strength and balance control. The impaired physical function results in poor quality of life and reduced community participation, leading to increased frailty and long-term disability. Further, compared to cognitively intact frail older adults, cognitively impaired frail older adults experience greater deterioration of such physical function, specifically during dual-task performances (i.e., simultaneous performance of cognitive and motor task). This deterioration occurs due to increased cognitive-motor interference as a result of dual-tasking and is known to increase exhaustion among frail older adults. Previous studies have used multicomponent training and have shown to improve physical function and maintain cardiovascular functioning. However, the capacity of such interventions to improve cognitive function along with physical function is not known or unclear. Further, the concurrent comorbidities that occur along with psychosocial issues such as depression present as barriers and lead to reduced compliance to therapy leaving only a few of them to benefit from it. Alternate forms of therapy such as exergaming with explicit cognitive training has shown promising effects in improving motor and motor function in disabled populations. These studies use a cost-effective, off the shelf device such as Nintendo Wii or Microsoft Kinect to deliver the training which is easily available and clinically translatable. Further, such training has demonstrated increase in brain connectivity enhancing cognitive functions associated with balance control. However, there is limited literature examining the effect of exergaming in older frail population and the efficacy of such training is unknown. Therefore, this study proposes a randomized controlled trial to examine the feasibility of CogXergaming program with an aim to improve locomotor-balance control, cognition, muscular system and cardiovascular fitness.
Age range
60 Years
Sex
ALL
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A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Change in 30-second Chair Stand Performance
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)
Change in Walking Performance
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)
Change in Cardiovascular Fitness
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)
Change in Physical Activity
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)
Change in Movement Velocity
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)
Change in End Point Excursion
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)
Change in Directional Control
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)
Change in Maximum Excursion
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)
Change in Postural Stability During Reactive Balance Control (Single and Dual-task)
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)
Change of Accuracy in Letter Number Sequencing
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)
Change in 4 Meter Walk Test
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)
Change in Spatial and Temporal Gait Parameters
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)
Change in Accuracy of Auditory Stroop
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)
Change in Dual-task Cost
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)
Change in Interference in the Reaction Time
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)
Change in Language Fluency
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)
Change in Reaction Time
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)
Change in Paired Associated Learning
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)
Change in Spatial Working Memory
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)
Change in Working Memory
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)
Change in Episodic Memory
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)
Change in Accuracy of Flanker Inhibitory Control and Attention Test
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)
Change in Cognitive Flexibility and Attention
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)
Change in Processing Speed
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)
Changes in Fractional Anisotropy
Timeframe: Baseline (Week 0) and Immediate Post-training (Week 8 for group A and week 10 for group B)