CompletedPhase 4

Topical Arnica and Mucopolysaccharide Polysulfate on Postoperative Pain, Edema and Trismus

Turkey (Türkiye)60 participantsStarted 2018-12-01

Plain-language summary

The present study was to evaluate the effect of topical Arnica and MPSP application with respect to visual analogue scale (VAS) scores, maximal interincisal opening (MIO) and edema values after mandibular impacted third molar removal on days 1, 3, 5 and 10 postoperatively. The following null hypotheses of the present research were determined as follows: usage of topical agents would not influence i) VAS scores, ii) MIO values, and iii) edema values on 1st, 3rd, 5th, and 10th days after the mandibular impacted third molar surgery

Who can participate

Age range16 Years – 68 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age between 16-68 years * American Society of Anesthesiologists (ASA) Class 1 physiological status * Consistent radiological and clinical data * Volunteered to participate in the study * Scale II" surgery difficulty according to Modified Parant Classification for mandibular impacted third molar removal, be free of pericoronitis and infection at operation time Exclusion Criteria: * Being out of age range * Pregnancy or lactation * Analgesic or antibiotic therapy history in last 14 days due to symptoms of related third molar * Smoking cigarette * Any pathology associated with impacted third molar * Active complaints on preoperative examination on the day of surgery * Immunosuppressed or diagnosed with malignancy * Diagnosed chronic diseases such as; Diabetes mellitus (DM), hypertension, cerebrovascular event, psychiatric diseases, coagulopathies * Autoimmune diseases * Patients who could not attend regular follow-up visits * Allergy to the medications prescribed or utilized in study protocol * Inconsistent clinical and radiological data or missed follow-up

What they're measuring

Preoperative Pain Intensity

Timeframe: On the day of surgery preoperatively

Change From Baseline Maximal Interincisal Opening (MIO) on Postoperative Follow Up Visits

Timeframe: Preoperatively on the day of surgery, postoperative first, third, fifth and tenth days

3. Change From Baseline Facial Measurements for Evaluation of Edema on Postoperative Follow Up Visits

Timeframe: Preoperatively on the day of surgery, postoperative first, third, fifth and tenth days

Trial details

NCT IDNCT04534426

SponsorAbant Izzet Baysal University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-12-01

View on ClinicalTrials.gov More Impacted Third Molar Tooth trials

Plain-language summary

Who can participate

Age range16 Years – 68 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Preoperative Pain Intensity

Timeframe: On the day of surgery preoperatively

Change From Baseline Maximal Interincisal Opening (MIO) on Postoperative Follow Up Visits

Timeframe: Preoperatively on the day of surgery, postoperative first, third, fifth and tenth days

3. Change From Baseline Facial Measurements for Evaluation of Edema on Postoperative Follow Up Visits

Timeframe: Preoperatively on the day of surgery, postoperative first, third, fifth and tenth days