TerminatedPhase 2

Microbiological Evaluation of Single Versus Multiple Visits Regeneration Using MALDI-TOF Mass Spectrometry

Stopped: due to the COVID-19 pandemic

Egypt16 participantsStarted 2018-08-23

Plain-language summary

Aim of the study is to assess canal disinfection using matrix assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) in single visit and multiple visit regeneration protocols, and to assess clinical and radiographic outcomes of single visit and multiple visit regeneration protocols.

Who can participate

Age range8 Years – 18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Immature permanent upper anterior teeth. * Necrotic teeth confirmed by sensibility test. * Teeth with periapical lesions confirmed by periapical radiograph using paralleling device. Exclusion Criteria: * Teeth with orthodontic wires or brackets. * Patient with history of allergy to any medication. * Patient with history of bleeding disorders. * Patient with medical illness or taking medications.

What they're measuring

Microbiological assessment

Timeframe: 24 hours

Tooth vitality

Timeframe: up to 12 months

Tooth mobility

Timeframe: up to 12 months

Healing of periapical lesions

Timeframe: up to 12 months

Root lengthening

Timeframe: up to 12 months

Root thickening

Timeframe: up to 12 months

Trial details

NCT IDNCT04533074

SponsorNourhan M.Aly

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-03-10

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