WithdrawnNot Applicable

Intraoperative Brain Microdialysis to Assess Neuroinflammation in Epileptic Tissue Immediately Prior to Surgical Resection.

Stopped: No subjects were enrolled and there was not funding to continue the study

United States0Started 2019-03-27

Plain-language summary

This research study will investigate the fluid from the area of the brain that is being removed during clinical epilepsy surgery. The goal is to analyze this fluid for inflammatory markers that can potentially help identify new strategies in the future to control seizures in individuals with epilepsy who fail to respond to currently available drugs.

Who can participate

Age range18 Years – 45 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria * Failure to respond to at least two trials of anti-seizure drugs with different mechanisms of action * Normal MRI Exclusion Criteria * Active immunomodulatory therapy * Autoimmune disorder * Signs or symptoms consistent with comorbid infection * Oncological comorbidity

What they're measuring

Detection of analytes/protein

Timeframe: Through study completion, up to 5 years

Trial details

NCT IDNCT04531722

SponsorMayo Clinic

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-01-10

View on ClinicalTrials.gov More Epilepsy trials