UnknownNot Applicable

His-bundle Pacing vs. Right Ventricular Apical Pacing in Patients With Reduced Ejection Fraction

Sweden40 participantsStarted 2020-12-01

Plain-language summary

The study compares standard right ventricle apical pacing with so called His-bundle pacing, for patients with slightly or moderately reduced ejection fraction and atrioventricular block requiring pacemaker therapy. The primary outcome is left ventricular ejection fraction measured after 6 months.

Who can participate

Age range18 Years – 100 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * AV block II or III with high expected pacing need * Left ventricular ejection fraction between 40% and 55% (inclusive) * Willing to participate and sign informed consent Exclusion Criteria: * Under 18 years old * Pregnant * Hypertrophic cardiomyopathy * Cardiac sarcoidosis * Cardiac amyloidosis * Previous myocardial infarction within last 3 months * Ventricular septum defect or other other left ventricular corrective surgery * Congenital heart disease surgically corrected * Atrial fibrillation with uncontrolled rate (if not planned for AV node ablation)

What they're measuring

Ejection Fraction

Timeframe: 6 months

Trial details

NCT IDNCT04529577

SponsorRegion Skane

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-12-01

Contact for this trial

Maiwand Farouq, MD, PhD

+ 46 40 336415‬ maiwand.farouq@skane.se

View on ClinicalTrials.gov More His Bundle Pacing trials