CompletedPhase 4

Airway Microbiota Based Treatment of Asthma in Preschool Children

China120 participantsStarted 2021-10-18

Plain-language summary

Airway microbiota pattern may related the preschool asthma exacerbation. This is a single-center, randomized-controlled trial, the study will compare the management of preschool wheeze determined by airway microbiota phenotype and blood eosinophils level to the management using current clinical guidelines.

Who can participate

Age range1 Year – 5 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * physician diagnosed recurrent wheeze（at least 3 episodes of wheezing or at least one course of oral steroids in the last 6 months） Exclusion Criteria: * Any congenital heart disease diagnosed by a physician * Any chronic respiratory condition other than preschool wheeze (bronchopulmonary dysplasia, bronchiolitis obliteran, congenital airway and lung malformations, bronchomalacia, chronic aspiration) diagnosed by a physician * Received antibiotic last 6 weeks

What they're measuring

Frequency of unscheduled healthcare visits for wheezing

Timeframe: from baseline to one year follow-up

Trial details

NCT IDNCT04527016

SponsorChildren's Hospital of Fudan University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-06-15

View on ClinicalTrials.gov More Asthma in Children trials