CompletedNot Applicable

Mechanical Thrombectomy for Acute Large Vessel Occlusion Stroke With Mild Symptoms

China105 participantsStarted 2016-07-01

Plain-language summary

Mechanical thrombectomy(MT) has been recommended in patients with acute large vessel occlusion stroke(LVO) , especially for those with National Institutes of Health Stroke Scale (NIHSS) score ≥6. However, it is still unclear if patients with minor strokes and LVO also benefit from MT.The aim of this study was to evaluate the safety and efficacy of MT for acute LVO and mild symptoms.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. acute ischemic stroke within 24 hours of symptom onset presenting cortical symptoms (such as aphasia, somnolence,slow-minded,etc.) or vertigo with bilateral pathological signs;
✓. age≥18 years old;
✓. the NIHSS score before evaluation of thrombectomy\<6;
✓. large artery occlusion including Middle cerebral artery M1, proximal M2 segment, intracranial internal carotid artery and infarct core volume≤50ml and mismatch ratio\>1.8 or basilar artery and posterior cerebral artery P1 occlusion

Exclusion criteria

✕. Patients without prior functional independence (mRS score of \>2)
✕. Patients in intervention group with occlusive artery spontaneous recanalization in digital subtraction angiography
✕. patients in control group with neurological worsening and received rescue thrombectomy

What they're measuring

modified Rankin Scale(mRS) score of 0 to 2

Timeframe: 90 days

Trial details

NCT IDNCT04526756

SponsorShanghai East Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-03-15

View on ClinicalTrials.gov More Ischemic Stroke trials