The Use of Triamcinolone Injection in Treatment of Refractory Benign Esophageal Stricture in Chil… (NCT04524897) | Clinical Trial Compass
UnknownPhase 4
The Use of Triamcinolone Injection in Treatment of Refractory Benign Esophageal Stricture in Children
20 participantsStarted 2020-12-01
Plain-language summary
To evaluate the efficacy of Intra-lesional triamcinolone injection in the management of refractory benign esophageal Stricture in children.
Who can participate
Age range
6 Months – 18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* All patients admitted to Assiut University Children Hospital with:
* refractory benign esophageal stricture(inability to successfully remediate the anatomic problem to a diameter of at least 14 mm over five sessions at two-week interval)
* inability to maintain a satisfactory luminal diameter for four weeks once the target diameter of 14 mm has been achieved
Exclusion Criteria:
* Pharyngeal stenosis precluding endoscopic examination and dilatation
* tracheo-esophageal fistula,
* gastric cicatrization that precluded safe placement of aguidewire
* any patient who was unfit for general anesthesia.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is measuring improvement in swallowing difficulty after five sessions of triamcinolone steroid injections — how does my child's current stricture severity compare to the children being treated in this study, and does that affect whether this approach might be worth discussing for them?
2Since this is a Phase 4 trial, the drug itself has already been approved, but its use specifically for refractory esophageal strictures in children is still being evaluated — what does that mean for how confident you are in its safety and effectiveness for my child's situation?
3The trial focuses on strictures that are 'refractory,' meaning they haven't responded well to standard treatment — has my child's stricture reached that point, and would you consider standard dilation approaches first before something like steroid injections?
4The recruitment status for this trial is listed as unknown, which may mean it's no longer actively enrolling — is this study still open, and if not, are there similar studies or centers using triamcinolone injections for pediatric esophageal strictures that we could look into?
5Five injection sessions is a significant commitment — what would the schedule, recovery time, and monitoring look like for my child, and how would we measure whether the treatment is actually working along the way?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
number of patients show improvement in dysphagia scale after five session of triamcinolone injection