In this investigation the investigators utilized NAC supplementation to boost GSH availability during an one-week-microcycle consisting of three soccer games, in order to test the hypotheses that: i) antioxidant supplementation may enhance the recovery of performance and physiological stress variables following multiple match-plays and ii) redox status perturbations are critical in regulating the inflammatory response and repair in skeletal muscle, following repetitive exercise-induced muscle injuries.
Age range
18 Years – 28 Years
Sex
MALE
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The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Change in total antioxidant capacity in serum
Timeframe: At baseline and daily throughout the study, up to 11 days
Change in protein carbonyls in serum
Timeframe: At baseline and daily throughout the study, up to 11 days
Change in thiobarbituric acid reactive substances in serum
Timeframe: At baseline and daily throughout the study, up to 11 days
Change in reduced glutathione in red blood cells
Timeframe: At baseline and daily throughout the study, up to 11 days
Change in oxidized glutathione in red blood cells
Timeframe: At baseline and daily throughout the study, up to 11 days
Change in creatine kinase in activity in plasma
Timeframe: At baseline and daily throughout the study, up to 11 days
Change in white blood cell count in blood
Timeframe: At baseline and daily throughout the study, up to 11 days
Change in repeated sprint ability
Timeframe: At baseline and daily throughout the study, up to 11 days
Change in high intensity running during the game
Timeframe: During games 1, 2 and 3