In this investigation the investigators utilized NAC supplementation to boost GSH availability during an one-week-microcycle consisting of three soccer games, in order to test the hypotheses that: i) antioxidant supplementation may enhance the recovery of performance and physiological stress variables following multiple match-plays and ii) redox status perturbations are critical in regulating the inflammatory response and repair in skeletal muscle, following repetitive exercise-induced muscle injuries.
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Change in total antioxidant capacity in serum
Timeframe: At baseline and daily throughout the study, up to 11 days
Change in protein carbonyls in serum
Timeframe: At baseline and daily throughout the study, up to 11 days
Change in thiobarbituric acid reactive substances in serum
Timeframe: At baseline and daily throughout the study, up to 11 days
Change in reduced glutathione in red blood cells
Timeframe: At baseline and daily throughout the study, up to 11 days
Change in oxidized glutathione in red blood cells
Timeframe: At baseline and daily throughout the study, up to 11 days
Change in creatine kinase in activity in plasma
Timeframe: At baseline and daily throughout the study, up to 11 days
Change in white blood cell count in blood
Timeframe: At baseline and daily throughout the study, up to 11 days
Change in repeated sprint ability
Timeframe: At baseline and daily throughout the study, up to 11 days
Change in high intensity running during the game
Timeframe: During games 1, 2 and 3