CompletedNot Applicable

Analysis of Intestinal Defensin Expression in Acute GVHD

Germany80 participantsStarted 2018-09-01

Plain-language summary

This study has the aim to analyze intestinal expression of endogenous antimicrobial peptides in patients with acute GVHD. The expression will be compared to intestinal expression of defensins in patients with colitis and patients without intestinal inflammation.

Who can participate

Age range18 Years – 99 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * age ≥ 18 years * diagnostic endoscopy was performed * diagnosis results available * written informed consent * ability to understand the nature of the study and the study related procedures and to comply with them Exclusion Criteria: * age \< 18 years * gastrointestinal cancer * lack of informed consent

What they're measuring

Defensin Expression (mRNA)

Timeframe: 3 years

Defensin Expression (peptide)

Timeframe: 3 years

Trial details

NCT IDNCT04522843

SponsorUniversity of Freiburg

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-10-30

View on ClinicalTrials.gov More GVHD,Acute trials