UnknownNot Applicable

Optimizing Antibiotic Dosing Regimens for the Treatment of Infection Caused by Carbapenem Resistant Enterobacteriaceae

Thailand102 participantsStarted 2020-09

Plain-language summary

The purpose of this study is to evaluate the treatment outcomes in patients with CRE infections.

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

✓. Any patients are diagnosed any diseases caused by CRE infection by physicians at Phramongkutklao hospital during 1/4/2018 to 30/4/2021.
✓. Any patients are more than 18 years old.
✓. Any patients have at least 1 criterion as following 3.1 Any patients have at least 2 of the signs and symptoms of Systemic inflammatory response syndrome (SIRS), including
✓.3. Any patients are diagnosed with septic shock or are received vasopressors (eg, dopamine, norepinephrine, epinephrine, vasopressin, phenylephrine), mean arterial pressure (MAP) \< 65 mm Hg, and lactate \> 2 mmol/L (18 mg/dL) 3.4 Any patients are received mechanical ventilation 3.5 Any patients are admitted at ICU ward.

✕. Patients are breast-feeding or pregnancy.
✕. Patients are insufficient or incomplete information on the medical electronic record such as patients transferred.

Clinical improvement or failure

Timeframe: up to 8 weeks

NCT IDNCT04516395

SponsorPhramongkutklao College of Medicine and Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-03

Wichai Santimaleeworagun, PhD